wget http://hgdownload.cse.ucsc.edu/admin/jksrc.zip
unzip jksrc.zip
cd kent/src/lib
echo $MACHTYPE
x86_64
export MACHTYPE=x86_64
make CXXFLAGS=-fPIC CFLAGS=-fPIC CPPFLAGS=-fPIC
cd..
export KENT_SRC=`pwd`
sudo perl -MCPAN -e 'install Bio::DB::BigFile'